Wednesday, August 26, 2009

Biocomputing & Bioinformatics loose notes

Laplante, P
Biocomputing

intro
vii Bioinformatics largely focuses on the analysis, prediction, imaging and sequencing of genes; broader field of Biocomputing includes study of biological models of computing using traditional materials, genomic modeling and visualizes biomaterials for non-traditional computer designs and computer architecture

Xiong, Jin
Essential Bioinformatics

3 Bioinformatics: quantitative analysis of information relating to biological macromolecules w/comptuers
4 Bioinformatics: interdisciplinary research area @ interface of computer sicence and biological sciences

4 Bioinfo limited to sequence, structural and functional analysis of genes

5 computational biology more theoretical development of algorithms used for bio info

GOAL of BioInfo
5 better understand a living cell and how it functions at the molecular level

Database
10 knowledge discovery--identification of connections between pieces of information that were not known when information was first entered
akin to protocol
how things relate vs. how they interact

11 relational db:
use table, column (field), rows (values)
columns are

object oriented db's
object: unit that combines data and routines that act on that data

Relational DBs
12 don't describe complex hierarchical relationship

31 sequence comparison at heart of BI analysis

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